Feb. 2026 N icholas O’Toole , Tie-Yuan Zhang , Eamon Fitzgerald , Xianglan Wen , Josie Diorio , Patricia P. Silveira , Benoit Labonté , Eric J. Nestler & Michael J Meaney ABSTRACT Background Chronic social defeat stress (CSDS) is a validated animal model for depression that produces sustained behavioral and transcriptional changes in the brain, notably the nucleus accumbens (nAcc). Research design and methods We used genome-wide analysis of cytosine methylation patterns in m

Feb. 2026 Jamshid Faraji, Gerlinde A.S. Metz Highlights Environmental factors strongly influence biological systems through epigenetic processes. Epigenetic mechanisms provide plasticity and resilience but can also mediate disease risk when dysregulated. Reversibility of epigenetic marks opens opportunities for targeted interventions and precision medicine. Ethical and policy considerations are critical as epigenetic screening and interventions expand. Transgenerational epige

Nov. 2025 Rachel Montel Hayes Christopher E. Mason John J. Miller The etiology of psychiatric disorders is complex, involving both genetic and environmental factors with emerging evidence suggesting that epigenetic modifications, including DNA methylation, histone modifications, and non-coding RNA regulation, significantly contribute to mental health. The epigenome influences the development of psychiatric disorders and human behavior and may be considered in clinical observa

July 20, 2025 This article provides a computational analysis of the behavioural effects of ADHD and its epigenetic factors including the...

July 20, 2025 Background/Objectives Digital technologies have become increasingly integrated into the daily lives of children and...

July 20, 2025 The potentially problematic use of the Internet is a growing concern worldwide, which causes and consequences are not...